Male fertility

Male fertility

I’m 22 years old and have cystic fibrosis. Luckily, I have no symptoms. Is it possible for men with a mild form of cystic fibrosis to be fertile?

Unfortunately, the infertility rate in men with cystic fibrosis is very high, whether they have a mild or severe form of the disease (95 to 99%, according to studies). Male carriers of the cystic fibrosis mutation whose lungs and digestive tracts are not affected by the disease still have the same type of sterility as men with cystic fibrosis: absence or degeneration of the vas deferens (the ducts that carry spermatozoa and seminal fluid from the testes to the penis).

Men with cystic fibrosis can, however, have biological children. Spermatozoa can be removed from the testes to fertilize the spouse’s oocytes (egg cells) in vitro. A fertilized oocyte can then be transferred to the uterus
and result in a normal birth. However, the procedure is costly (about $20,000), and success is not guaranteed.

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